ABSTRACT
One new flavonoid named 5, 7-dihydroxy-3,6,3'-trimethoxyflavone [1], together with eight known phenolic compounds; 3,4-dihydroxy methyl benzoate [2], 3,4-dihydroxybenzoic acid [3], isorhamnetin [4], quercetin [5], myricetin [6,], isorhamnetin-4'-O-beta-D-glucopyranoside [7], quercettn-4'-O-beta-D-g/ucopyranoside [8] and quercetin-3,4'-O-beta-D-diglucopyranoside [9] were isolated from the flowers of Cucurbita pepo L. for the first time except 3 which was previously isolated from the plant. Their structures have been established on the basis of physical, chemical and spectroscopic methods in addition to comparison with literature data and/or authentic samples. The met hanolic and ethyl acetate extracts were evaluated for their antimicrobial activity